Pharmacological and clinical profiles of galantamine (Reminyl®)
نویسندگان
چکیده
منابع مشابه
Long-term benefits of galantamine (Reminyl) in Alzheimer’s disease
The natural history of Alzheimer’s disease, combined with recognition of the advantages of introducing specific treatment early in the course of the disease, means that patients may take medication for several years. Previous studies of galantamine (Reminyl) have shown an excellent record of safety and efficacy over 12 months with a broad spectrum of benefits that includes functional and behavi...
متن کاملPharmacological investigations of new galantamine peptide esters
Galantamine hydrobromide (GAL) is a reversible acetylcholinesterase inhibitor, with properties to increase the concentration of acetylcholine in several brain structures. The aim of this study is to determine the effect of new galantamine peptide esters: 3,4-dichlorophenyl-alanil-leucil-glycine-galantamine (GAL-LEU) and 3,4-dichlorophenyl-alanil-valil-glycine-galantamine (GAL-VAL), on locomotor...
متن کاملPharmacological aspects of galantamine for the treatment of Alzheimer's disease
Galantamine is a natural product belonging to the isoquinoline alkaloid family of compounds. It was first discovered and isolated in the 1950s from Galanthus nivalis (common snowdrop) and Galanthus woronowii (Caucasian snowdrop), members of the Amaryllidaceae family (Marco and do Carmo Carreiras, 2006). Alzheimer’s disease (AD) is named after Dr. Alois Alzheimer, who first identified the diseas...
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BACKGROUND To assess the sensitivity of biochemical, physiological, and pharmacological markers of peripheral norepinephrine (NE) transporter (NET) function, we chronically antagonized NET by a range of doses of duloxetine [(+)-N-methyl-3-(1-naphthalenyloxy)-2 thiophenepropanamine], which blocks the NE reuptake process. METHODS AND RESULTS Duloxetine was administered in a randomized, placebo-...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2011
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.138.122